Biomedical Core
Joseph P. Gaut, MD, PhD
Ladenson Professor of Pathology, Pathology and Immunology
Division Chief, Anatomic and Molecular Pathology
Washington University in St. Louis School of Medicine
Joseph Gaut, MD, PhD is the Ladenson Professor of Pathology and Immunology, the Division Chief of Anatomic and Molecular Pathology, and the Medical Director of the Barnes-Jewish Hospital Histology Laboratory. Gaut received his MD and PhD degrees from Washington University School of Medicine. He completed an internship in General Surgery at Barnes Hospital/Washington University and a post-doctoral fellowship at Washington University with Jack Ladenson, PhD. He completed his Anatomic Pathology residency at Massachusetts General Hospital, Clinical Pathology residency at Washington University, and fellowships in renal and surgical pathology at Washington University. Gaut’s clinical focus is in the area of renal pathology. His research is focused on improved diagnostic methods for renal disease. He has published extensively in genetic glomerular disease, acute kidney injury (AKI) pathology, and emerging AKI biomarkers. More recently, Gaut has investigated image analysis methods for evaluation of organ quality prior to transplantation. He has collaborated on several consortia projects including the Kidney Precision Medicine Project and the Human Biomolecular Atlas Program.
Sanjay Jain, MD, PhD
Professor of Medicine, Nephrology
Professor of Pediatrics, Molecular Genetics and Genomics Program
Director Kidney Translational Research Center
Washington University in St. Louis School of Medicine
Sanjay Jain is a Professor of Medicine, Pediatrics and Pathology & Immunology at the Washington University School of Medicine in St. Louis, Missouri, USA (WUSM). His laboratory focuses on how kidneys and the lower urinary tract develop and organize to maintain homeostasis across lifespan in health and disease. His has defined key developmental pathways and mechanisms that regulate the joining of primitive ureter and bladder, initiation of the collecting system and branching morphogenesis of the kidney and genetic mutations associated with CAKUT. He leads multiple NIH-sponsored atlas efforts to map healthy and disease states in the human kidney including HuBMAP, KPMP, RBK/GUDMAP and Pediatric Center of Excellence in Nephrology. The team has identified, validated and mapped ~100 cell identities in the kidney including healthy and injured cells and defined genes and pathways that help recovery or predict decline in kidney function.